18+ · Research Use Only · Not for Human Consumption
The longevity research stack: substrate, signal, and structure.
NAD+, MOTS-c and GHK-Cu each occupy a different layer of aging research. Here is the logic that connects them, and the peso pricing for all three.
The substrate layer: NAD+
NAD+ is the foundation of the stack because it is not a signal, it is a substrate. The molecule sits at the center of cellular redox chemistry, and it is consumed by the enzyme families that dominate aging research: sirtuins, which regulate stress response and metabolism, and PARP enzymes, which run DNA repair. Cellular NAD+ levels decline measurably with age, and the research thesis, covered in depth in the NAD+ deep dive, asks what restoring those levels changes.
The catalogue carries NAD+ as a 1000mg vial at ₱2,790, or ₱2,510 on a first order. That is the molecule itself, not a precursor: the distinction from NMN supplement capsules is its own topic.
The signaling layer: MOTS-c
One level up from substrate chemistry sits mitochondrial signaling. MOTS-c is a peptide encoded in mitochondrial DNA itself, studied in rodent models for AMPK activation and metabolic stress response, the same energy-sensing pathway exercise activates. Aging research is interested in MOTS-c because mitochondrial function is one of the most consistent casualties of aging, and a mitochondrially derived signal is a direct way to probe it.
NAD+ and MOTS-c make a natural research pairing: one supplies the substrate mitochondrial enzymes consume, the other probes the signaling that governs mitochondrial behavior. The two layers are contrasted properly in MOTS-c versus NAD+. MOTS-c ships as a 20mg vial at ₱1,980, ₱1,780 first order, and it sells through fast.
The structural layer: GHK-Cu, and the stack in practice
The third layer is structural. GHK-Cu, the copper-binding tripeptide, is studied for collagen synthesis and tissue remodeling gene expression, the visible, structural side of aging biology that substrate and signaling work does not touch. Its concentration in human plasma also declines sharply with age, which is why it keeps appearing in longevity literature alongside the other two. The 50mg vial is the most affordable slot in the stack at ₱1,140, or ₱1,030 first order.
The framing, as always: stacks describe how research protocols combine compounds across layers of a question, never personal-use guidance. All three are supplied for laboratory research only. Ordered together on a first order the trio comes to ₱5,320, shipped from Metro Manila cold storage with batch-numbered labels, same day in the metro before the noon cutoff, 1 to 3 days nationwide by insulated courier.
Supplied for laboratory research use only. Not for human consumption. Nothing on this page is medical advice.
Longevity stack questions
What is in the longevity research stack?
The catalogue's longevity trio is NAD+ as the redox substrate, MOTS-c as the mitochondrial signaling peptide, and GHK-Cu for the tissue remodeling layer. Research protocols combine them because each addresses a different layer of aging biology.
What does the longevity stack cost?
NAD+ 1000mg is ₱2,790, or ₱2,510 first order. GHK-Cu 50mg is ₱1,140, or ₱1,030 first order. MOTS-c 20mg is ₱1,980, or ₱1,780 first order. All three on a first order come to ₱5,320.
Why NAD+ instead of an NMN supplement?
NMN is a precursor the cell must convert. Research protocols that study NAD+ directly use the molecule itself, which is why the catalogue carries a 1000mg NAD+ vial rather than capsules. The comparison post covers the difference in full.
Do the three compounds have overlapping mechanisms?
Minimally, which is the point. NAD+ is a substrate consumed by sirtuins and PARP enzymes, MOTS-c signals through AMPK, and GHK-Cu is studied for collagen and remodeling gene expression. Protocols layer them to cover distinct mechanisms rather than to double up on one.